A representative listing of journal articles and other published research reporting how diet formulas have been used in research.
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Bekhor, I., Shi, S., Unakar, N. J. (1990) Management of aldose reductase messenger RNA abundance in rat lens undergoing reversal of galactose induced cataracts a model for gene response to changes in the environment. Mol Cell Biochem 95(1): 55-60. |
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Breckenridge, W. C., Roberts, A., Kuksis, A. (1985) Lipoprotein levels in genetically selected mice with increased susceptibility to atherosclerosis. Arteriosclerosis 5(3): 256-264. |
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Carey, K. D., McGill, H. C., Fless, G. M., Ackson, E., Anu, A. M., Khalil, A., Neven, L., Tidore, M., Dawson, G., Pfaffinger (1988) Genetically determined hypercholesterolemia in a Rhesus monkey family due to a deficiency of the LDL receptor. J Lipid Res 29(12): 1671-1682. |
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Challis, B. G., et al. Mice lacking pro-opiomelanocortin are sensitive to high-fat feeding but respond normally to the acute anorectic effects of peptide-YY3Ð36. PNAS 101: 13: 4695Ð4700, 2004. |
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Chouinard RA Jr, Luo Y, Osborne TF, Walsh A, and Tall AR. Sterol regulatory element binding protein-1 activates the cholesterol ester transfer protein gene in vivo but is not required for sterol up-regulation of gene expression. J. Biol. Chem. 273:22409-22414, 1998. |
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Combs, T. P., et al. A Transgenic Mouse with a Deletion in the Collagenous Domain of Adiponectin Displays Elevated Circulating Adiponectin and Improved Insulin Sensitivity. Endocrinology 145:367Ð383, 2004. |
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Conarello, S. L., et al. Mice lacking dipeptidyl peptidase IV are protected against obesity and insulin resistance. PNAS, 100:11: 6825Ð6830, 2003. |
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Dube MG, Beretta E, Dhillon H, Ueno N, Kalra PS & Kalra SP. Central Leptin Gene Therapy Blocks High-Fat Diet-Induced Weight Gain, Hyperleptinemeia, and Hyperinsulinemia. Diabetes 51:1729-1736, 2001. |
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El-Haschimi, K., S. D. Dufresne, M. F. Hirshman, J. S. Flier, L. J. Goodyear, and C. Bj¿rb¾k. Insulin Resistance and Lipodystrophy in Mice Lacking Ribosomal S6 Kinase 2. Diabetes 52:1340Ð1346, 2003. |
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Felipe, F., M.L. Bonet, J. Ribot and A. Palou. Up-regulation of muscle uncoupling protein 3 gene expression in mice following high fat diet, dietary vitamin A supplementation and acute retinoic acid-treatment. International Journal of Obesity 27: 60Ð69, 2003. |
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Ho, A., Chin, A. (1988) Circadian feeding and drinking patterns of genetically obese mice fed solid chow diet. Physiol Behav 43(5): 651-656. |
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Joseph, J. W., V. Koshkin, C-Y Zhang, J. Wang, B. B. Lowell, C. B. Chan, and M.B. Wheeler. Uncoupling Protein 2 Knockout Mice Have Enhanced Insulin Secretory Capacity After a High-Fat Diet. Diabetes 51:3211Ð3219, 2002. |
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Kim, S., et al. Effects of High-Fat, Angiotensinogen (agt) Gene Inactivation, and Targeted Expression to Adipose Tissue on Lipid Metabolism and Renal Gene Expression. Horm Metab Res 34:721-725, 2002. |
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Kohara, K., Brosnihan, K. B., Ferrario, C. M., Milsted, A. (1992) Peripheral and central angiotensin II regulates expression of genes of the renin-angiotensin system. American J of Physiology 262(5), Part 1: E651-657. |
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Lauterio, T. J., Aravich, P. F., Rotivein, P. (1990) Divergent Effects of insulin on insulin-like growth factor-II gene expression in the rat hypothalamus. Endocrinology 126(1): 392-398. |
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Le Laya, S., et al. Decreased Resistin Expression in Mice with Different Sensitivities to a High-Fat Diet. Biochemical and Biophysical Research Communications 289:2:564-567, 2001. |
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Li, J., K. Takaishi, W. Cook, S. K. McCorkle, and R. H. Unger. Insig-1 ÔÔbrakesÕÕ lipogenesis in adipocytes and inhibits differentiation of preadipocytes. PNAS 100:16:9476Ð9481, 2003. |
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Lichtman AH, Clinton S et al. Hyperlipidemia and Atherosclerosclerotic Lesion Development in LDL Receptor-Deficient Mice Fed Defined Semi purified Diets With and Without Cholate. Arteriosclerosis, Thrombosis and Vascular Biology. 1999; 19:1938-1944. |
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Ludwig, D. S., et al. Melanin-concentrating hormone overexpression in transgenic mice leads to obesity and insulin resistance. J. Clin. Invest. 107:379Ð386, 2001. |
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Masuzaki H, Paterson J, Shinyama H, Morton NM, Mullins JJ, Seckl JR, Flier JS. A Transgenic Model of Visceral Obesity and the Metabolic Syndrome. Science. 2001; 294:2166-2170. |
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Moon, Y. S., et al. Mice Lacking Paternally Expressed Pref-1/Dlk1 Display Growth Retardation and Accelerated Adiposity. Molecular And Cellular Biology 22:15: 5585Ð5592, 2002. |
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Murray I, Havel PJ, Sniderman AD & Cianflone K. Reduced Body Weight, Adipose Tissue, and Leptin Levels Despite Increased Energy Intake in Female Mice Lacking Acylation-Stimulating Protein. Endocrinology. 141:1041-1049; 2000 |
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Murray I, Sniderman AD, Havel PJ & Cianflone K. Acylation Stimulating Protein (ASP) Deficiency Alters Postprandial and Adipose Tissue Metabolism in Male Mice. Journal of Biological Chemistry. 1999 |
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Murray, I., A. D. Sniderman, P. J. Havel, and K. Cianflonei. Acylation Stimulating Protein (ASP) Deficiency Alters Postprandial and Adipose Tissue Metabolism in Male Mice. The Journal Of Biological Chemistry 274:51:36219Ð36225, 1999. |
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Noga AA, Zhao Y, and Vance DE. An Unexpected Requirement for Phosphatidylethanolamine N-Methyltransferase in the Secretion of Very Low Density Lipoproteins. J. Biol. Chem., Oct 2002; 277: 42358 - 42365 ; 10.1074/jbc.M204542200. |
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Nonogaki K, et al. Leptin-independent hyperphagia and type 2 diabetes in mice with a mutated serotonin 5-HT2C receptor gene. Nature Medicine 1998; 4:1152-1156. |
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Oberbauer, A. M., Currier, T. A., Nancarrow, C. D., Ward, K. A., Murray, J. D. (1992) Linear bone growth of oMTLa-oGH transgenic male mice. American J of Physiology 262(6), Part 1: E936-942. |
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Ogilvie, K. M., R. Saladin, T. R. Nagy, M. S. Urcan, R. A. Heyman, and M. D. Leibowitz. Activation of the Retinoid X Receptor Suppresses Appetite in the Rat. Endocrinology 145:565Ð573, 2004. |
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Omez, R. A., Chevalier, R. L., Everett, A. D., Elwood, J. P., Peach, M. J., Lynch, K. R., Carey, R. M. (1990) Recruitment of renin gene-expressing cells in adult rat kidneys. American J of Physiology 259(4): F660-665. |
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Pagliassotti MJ, Knobel SM, Shahrokhi KA, & Hill JO. Time course of adaptation to a high-fat diet in obesity-resistant and obesity-prone rats. Am. J. Physiol. 267:R659-R664, 1994 |
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Pagliassotti MJ, Shahrokhi KA, & Hill JO. Skeletal muscle glucose metabolism in obesity-prone abd obesity-resistant rats. Am. J. Physiol. 264:R1224-R1228, 1993. 7. |
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Paigen B, et al. Variation in susceptibility to atherosclerosis among inbred strains of mice. Atherosclerosis. 57:65-73, 1985. |
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Park EI, Paisley EA, Mangian HJ, Swartz DA, Wu M, O'Morchoe PJ, Behr SR, Visek WJ & Kaput J. Lipid Level and Typr Alter Stearoyl CoA Desaturase mRNA Abundance Differently in Mice with Distinct Susceptibilities to Diet-Influenced Diseases. J Nutr. 127: 566-573; 1997 |
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Phan,L. K., F. Lin, C. A. LeDuc, W. K. Chung, and R. L. Leibel. The mouse mahoganoid coat color mutation disrupts a novel C3HC4 RING domain protein. J. Clin. Invest. 110:1449Ð1459, 2002. |
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Pratico D, et al. Vitamin E suppresses isoprostane generation in vivo and reduces atherosclerosis in ApoE-deficient mice. Nat. Med. 4:1189-92, 1998. |
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Prins, G. A. (1992) Neonatal estrogen exposure induces lobe-specific alterations in adult rat prostrate androgen receptor expression. Endocrinology 130(6): 3703-3714. |
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Razani B, Combs TP, Wang XB, Frank PG, Park DS, Russell RG, Li M, Tang B, Jelicks LA, Scherer PE, Lisanti MP. Caveolin-1 deficient mice are lean, resistant to diet-induced obesity, and show hyper-triglyceridemia with adipocyte abnormalities. J Biol. Chem., Mar 2002; 277: 8635 - 8647 ; 10.1074/jbc.M110970200 |
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Sahu, A., Phelps, C. P., White, J. D., Crowley, W. R., Kalra, S. P., Kalra, P. S. (1992) Steroidal regulation of hypothalmic neuropeptide Y release and gene expression. Endocrinology 130(6): 3331-3336. |
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Schmid, R. M., Meisler, M. G. (1992) Dietary regulation of pancreatic amylase in transgenic mice mediated by a 126-base pair DNA fragment. American J of Physiology 262(6), Part 1: G971-976. |
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Shklyaev, S., et al. Sustained peripheral expression of transgene adiponectin offsets the development of diet-induced obesity in rats. PNAS 100:24:14217Ð14222, 2003. |
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Takahashi, N., et al. Divergent Effects of Leptin in Mice Susceptible or Resistant to Obesity. Horm Metab Res 34:691-697, 2002. |
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Tyan, M. L. (1992) Effects of H-2 and vitamin A on micrognathia in congenic mice. Proc Soc Exp Biol Med 200(3): 418-421. |
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Tyan, M. L. (1995) Effects of vitamin A and inositol on term weights of H-2 congenic mice. Proc Soc Exp Biol Med 210(1): 77-80. |
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Tyan, M. L., Tyan, D. B. (1993) Vitamin A-enhanced cleft palate susceptibility gene maps between C4 and B144 within the H-2 complex. Proc Soc Exp Biol Med 202(4): 482-486. |
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Valet P, Grujic D, Wade J, Ito M, Zingaretti MC, Soloveva V, Ross SR, Graves RA, Cinti S, Lafontan M, and Lowell BB. Expression of human alpha 2-adrenergic receptors in adipose tissue of beta 3-adrenergic receptor-deficient mice promotes diet-induced obesity. J.Biol.Chem. 275: 34797-34802, 2000. |
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Vidal-Puig AJ, Grujic D, Zhang CY, Hagen T, Boss O, Ido Y, Szczepanik A, Wade J, Mootha V, Cortright R, Muoio DM, and Lowell BB. Energy metabolism in uncoupling protein 3 gene knockout mice. J.Biol.Chem. 275: 16258-16266, 2000. |
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Yamashita, T., et al. Enhanced insulin sensitivity in mice lacking ganglioside GM3. PNAS 100:6:3445Ð3449, 2003. |