Rats – Care, Feeding, & Physiology
Care and Feeding |
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Number of Adults |
Number
of |
Cage Dimensions* |
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Length |
Width |
Height |
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Breeding/Lactation |
1 female |
8 |
30 cm |
20 cm |
20 cm |
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Growing |
10-15 |
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60 cm |
50 cm |
25 cm |
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Experimental |
Varies according to experiment |
Variable |
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Feeding Recommendations |
Daily Feed Usage |
Fisher |
Larger
Strains** |
Water Requirement |
Begin Dry Food Consumption |
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Adult
Male |
12-15 gm |
20-35 gm |
Ad libitum |
12 days |
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Environmental
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Room Temp. |
Humidity |
Light |
Litter Material |
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21-27 ¡C |
45-55% |
12 hrs/day |
Shavings, beet pulp, corn cob, commercial bedding |
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Biological Values |
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Blood Chemical Composition |
Water |
Calcium |
Sodium |
Chloride |
Phosphorus |
Potassium |
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92-94 gm/100ml |
6.2 mEq/L |
144 mEq/L |
110 mEq/L |
5.9 mg/100ml |
5.9 mEq/L |
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Values
are for plasma, |
Magnesium |
Cholesterol |
Glucose |
Serum Protein |
Albumin |
Globulin |
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1.6 mg/100ml |
28-76 mg/100ml |
56-76 mg/100ml (whole blood) |
6.3 gm/100ml |
3.4-4.3 gm/100ml |
1.8-2.5 gm/100ml |
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Oxygen Consumption and Body Temperature |
Observed |
Temp- |
Oxygen
Consum- |
Breathing Rate |
Heart
Beat |
Heart
Beat |
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250 gm |
38.2 ¡C |
0.88 mlO2/gm/hr |
94/minute |
382/minute |
161/minute |
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Hematological Values |
Whole
Blood Volume |
Clotting Time |
RBC Life Span |
RBC Diameter |
RBC
Rate of |
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58 ml/kg |
20 sec. |
45-68 days |
6.8 microns |
0.7-1.8 mm/hr |
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Blood pH |
RBC |
Hematocrit |
Platelets |
Hb |
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7.35 |
7.2-9.6 106/mm3 |
46 ml/100ml |
706-796 103/mm3 |
14.8 gm/100ml |
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Total and Differential White Blood Cell Counts |
Leucocytes |
Neutros |
Eosinos |
Basos |
Lymphos |
Monos |
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14.0 103/mm3 |
3.1 103/mm3 |
0.3 103/mm3 |
0.10 103/mm3 |
10.2 103/mm3 |
0.30 103/mm3 |
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Life Cycle Information |
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Weight |
Weight |
Weight |
Breeding
Age |
Breeding Age Female |
Estrus |
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300-400 gm |
250-300 gm |
5-6 gm |
100 days |
100 days |
5 days |
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Gestation |
Weaning Age |
Litter Size |
Rebreed After Parturition |
Breeding Life Male |
Breeding Life Female |
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20-22
days |
21 days |
8-12 |
Immediately |
1 Year |
1 Year |
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Mating Data: Pair or colony: 1 male, 10 females |
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* |
Refer to the "Guide for the Care and use of Laboratory Animals" - NIH Publication No. 85-23, Revised 1985. |
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Prepared by the Institute of Laboratory Animal Resources, National Research Council, 2101 Constitution Avenue, N.W., Washington, DC 20418 |
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** |
Depends on Strain of rats. Some Investigators restrict the feed of ÒSprague DawleyÓ rats. Levels of 21-22 gr/day for male rats and 16-17 gr/day for female rats are levels of feed restrictions frequently used. See Portion-Controlled Diets |