Rats – Care, Feeding, & Physiology

Care and Feeding


 

Number of Adults

Number of
Young

Cage Dimensions*

Length

Width

Height

Breeding/Lactation

1 female

8

30 cm

20 cm

20 cm

Growing

10-15

 

60 cm

50 cm

25 cm

Experimental

Varies according to experiment

Variable


Feeding Recommendations

Daily Feed Usage

Fisher
Ad-libitum

Larger Strains**
Ad libitum

Water Requirement

Begin Dry Food Consumption

Adult Male
Adult Female
Preg. & Lactating Females
Growing Male
Growing Females

12-15 gm
12-15 gm
30-40 gm
12-15 gm
12-15 gm

20-35 gm
15-25 gm
30-55 gm
15-30 gm
14-22 gm

Ad libitum

12 days


Environmental
Data

Room Temp.

Humidity

Light

Litter Material

21-27 ¡C

45-55%

12 hrs/day

Shavings, beet pulp, corn cob, commercial bedding

Biological Values


Blood Chemical Composition

Water

Calcium

Sodium

Chloride

Phosphorus

Potassium

92-94 gm/100ml

6.2 mEq/L

144 mEq/L

110 mEq/L

5.9 mg/100ml

5.9 mEq/L

Values are for plasma,
except where noted

Magnesium

Cholesterol

Glucose

Serum Protein

Albumin

Globulin

1.6 mg/100ml

28-76 mg/100ml

56-76 mg/100ml (whole blood)

6.3 gm/100ml

3.4-4.3 gm/100ml

1.8-2.5 gm/100ml


Oxygen Consumption and Body Temperature

Observed
Weight

Temp-
erature

Oxygen Consum-
ption

Breathing Rate

Heart Beat
Adult

Heart Beat
Newborn

250 gm

38.2 ¡C

0.88 mlO2/gm/hr

94/minute
(75-115)

382/minute
(261-600)

161/minute
(81-241)


Hematological Values

Whole Blood Volume
(T-1824 dye)

Clotting Time

RBC Life Span

RBC Diameter

RBC Rate of
Sedimentation

58 ml/kg

20 sec.

45-68 days

6.8 microns

0.7-1.8 mm/hr

Blood pH

RBC

Hematocrit

Platelets

Hb

7.35

7.2-9.6 106/mm3

46 ml/100ml

706-796 103/mm3

14.8 gm/100ml


Total and Differential White Blood Cell Counts

Leucocytes

Neutros

Eosinos

Basos

Lymphos

Monos

14.0 103/mm3

3.1 103/mm3

0.3 103/mm3

0.10 103/mm3

10.2 103/mm3

0.30 103/mm3

Life Cycle Information


 

Weight
Adult Male

Weight
Adult Female

Weight
at Birth

Breeding Age
Male

Breeding Age Female

Estrus
Cycle

 

300-400 gm

250-300 gm

5-6 gm

100 days
300 gm

100 days
200 gm

5 days

 

Gestation

Weaning Age

Litter Size

Rebreed After Parturition

Breeding Life Male

Breeding Life Female

 

20-22 days
21 days avg,

21 days
40-50 gm

8-12

Immediately

1 Year

1 Year

 

Mating Data: Pair or colony: 1 male, 10 females

*

Refer to the "Guide for the Care and use of Laboratory Animals" - NIH Publication No. 85-23, Revised 1985.

 

Prepared by the Institute of Laboratory Animal Resources, National Research Council, 2101 Constitution Avenue, N.W., Washington, DC 20418

**

Depends on Strain of rats. Some Investigators restrict the feed of ÒSprague DawleyÓ rats. Levels of 21-22 gr/day for male rats and 16-17 gr/day for female rats are levels of feed restrictions frequently used. See Portion-Controlled Diets

 

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